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\left(-16x-4\right)\left(4x-1\right)
Use the distributive property to multiply -4 by 4x+1.
-64x^{2}+16x-16x+4
Apply the distributive property by multiplying each term of -16x-4 by each term of 4x-1.
-64x^{2}+4
Combine 16x and -16x to get 0.
\left(-16x-4\right)\left(4x-1\right)
Use the distributive property to multiply -4 by 4x+1.
-64x^{2}+16x-16x+4
Apply the distributive property by multiplying each term of -16x-4 by each term of 4x-1.
-64x^{2}+4
Combine 16x and -16x to get 0.