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Evaluate
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Differentiate w.r.t. b
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\left(-2^{4}\left(a^{4}\right)^{4}\left(b^{5}\right)^{4}\right)\times \left(16a^{4}b^{5}\right)^{0}
Expand \left(2a^{4}b^{5}\right)^{4}.
\left(-2^{4}a^{16}\left(b^{5}\right)^{4}\right)\times \left(16a^{4}b^{5}\right)^{0}
To raise a power to another power, multiply the exponents. Multiply 4 and 4 to get 16.
\left(-2^{4}a^{16}b^{20}\right)\times \left(16a^{4}b^{5}\right)^{0}
To raise a power to another power, multiply the exponents. Multiply 5 and 4 to get 20.
\left(-16a^{16}b^{20}\right)\times \left(16a^{4}b^{5}\right)^{0}
Calculate 2 to the power of 4 and get 16.
\left(-16a^{16}b^{20}\right)\times 1
Calculate 16a^{4}b^{5} to the power of 0 and get 1.
-16a^{16}b^{20}
Multiply -1 and 16 to get -16.