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-\frac{16777216}{531441}\left(-\frac{9}{16}\right)^{6}
Calculate \frac{4}{3} to the power of 12 and get \frac{16777216}{531441}.
-\frac{16777216}{531441}\times \frac{531441}{16777216}
Calculate -\frac{9}{16} to the power of 6 and get \frac{531441}{16777216}.
\frac{-16777216\times 531441}{531441\times 16777216}
Multiply -\frac{16777216}{531441} times \frac{531441}{16777216} by multiplying numerator times numerator and denominator times denominator.
\frac{-16777216}{16777216}
Cancel out 531441 in both numerator and denominator.
-1
Divide -16777216 by 16777216 to get -1.