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\frac{-\frac{4\left(x+1\right)}{x^{2}+4x}}{\frac{9x}{\left(x-4\right)\left(x+4\right)}-\frac{x+4}{x\left(x-4\right)}}
Factor x^{2}-16. Factor x^{2}-4x.
\frac{-\frac{4\left(x+1\right)}{x^{2}+4x}}{\frac{9xx}{x\left(x-4\right)\left(x+4\right)}-\frac{\left(x+4\right)\left(x+4\right)}{x\left(x-4\right)\left(x+4\right)}}
To add or subtract expressions, expand them to make their denominators the same. Least common multiple of \left(x-4\right)\left(x+4\right) and x\left(x-4\right) is x\left(x-4\right)\left(x+4\right). Multiply \frac{9x}{\left(x-4\right)\left(x+4\right)} times \frac{x}{x}. Multiply \frac{x+4}{x\left(x-4\right)} times \frac{x+4}{x+4}.
\frac{-\frac{4\left(x+1\right)}{x^{2}+4x}}{\frac{9xx-\left(x+4\right)\left(x+4\right)}{x\left(x-4\right)\left(x+4\right)}}
Since \frac{9xx}{x\left(x-4\right)\left(x+4\right)} and \frac{\left(x+4\right)\left(x+4\right)}{x\left(x-4\right)\left(x+4\right)} have the same denominator, subtract them by subtracting their numerators.
\frac{-\frac{4\left(x+1\right)}{x^{2}+4x}}{\frac{9x^{2}-x^{2}-4x-4x-16}{x\left(x-4\right)\left(x+4\right)}}
Do the multiplications in 9xx-\left(x+4\right)\left(x+4\right).
\frac{-\frac{4\left(x+1\right)}{x^{2}+4x}}{\frac{8x^{2}-8x-16}{x\left(x-4\right)\left(x+4\right)}}
Combine like terms in 9x^{2}-x^{2}-4x-4x-16.
\frac{\left(-\frac{4\left(x+1\right)}{x^{2}+4x}\right)x\left(x-4\right)\left(x+4\right)}{8x^{2}-8x-16}
Divide -\frac{4\left(x+1\right)}{x^{2}+4x} by \frac{8x^{2}-8x-16}{x\left(x-4\right)\left(x+4\right)} by multiplying -\frac{4\left(x+1\right)}{x^{2}+4x} by the reciprocal of \frac{8x^{2}-8x-16}{x\left(x-4\right)\left(x+4\right)}.
\frac{\frac{-4\left(x+1\right)x}{x^{2}+4x}\left(x-4\right)\left(x+4\right)}{8x^{2}-8x-16}
Express \left(-\frac{4\left(x+1\right)}{x^{2}+4x}\right)x as a single fraction.
\frac{\frac{-4\left(x+1\right)x\left(x-4\right)}{x^{2}+4x}\left(x+4\right)}{8x^{2}-8x-16}
Express \frac{-4\left(x+1\right)x}{x^{2}+4x}\left(x-4\right) as a single fraction.
\frac{\frac{-4\left(x+1\right)x\left(x-4\right)\left(x+4\right)}{x^{2}+4x}}{8x^{2}-8x-16}
Express \frac{-4\left(x+1\right)x\left(x-4\right)}{x^{2}+4x}\left(x+4\right) as a single fraction.
\frac{-4\left(x+1\right)x\left(x-4\right)\left(x+4\right)}{\left(x^{2}+4x\right)\left(8x^{2}-8x-16\right)}
Express \frac{\frac{-4\left(x+1\right)x\left(x-4\right)\left(x+4\right)}{x^{2}+4x}}{8x^{2}-8x-16} as a single fraction.
\frac{-4x\left(x-4\right)\left(x+1\right)\left(x+4\right)}{8x\left(x-2\right)\left(x+1\right)\left(x+4\right)}
Factor the expressions that are not already factored.
\frac{-\left(x-4\right)}{2\left(x-2\right)}
Cancel out 4x\left(x+1\right)\left(x+4\right) in both numerator and denominator.
\frac{-x+4}{2x-4}
Expand the expression.
\frac{-\frac{4\left(x+1\right)}{x^{2}+4x}}{\frac{9x}{\left(x-4\right)\left(x+4\right)}-\frac{x+4}{x\left(x-4\right)}}
Factor x^{2}-16. Factor x^{2}-4x.
\frac{-\frac{4\left(x+1\right)}{x^{2}+4x}}{\frac{9xx}{x\left(x-4\right)\left(x+4\right)}-\frac{\left(x+4\right)\left(x+4\right)}{x\left(x-4\right)\left(x+4\right)}}
To add or subtract expressions, expand them to make their denominators the same. Least common multiple of \left(x-4\right)\left(x+4\right) and x\left(x-4\right) is x\left(x-4\right)\left(x+4\right). Multiply \frac{9x}{\left(x-4\right)\left(x+4\right)} times \frac{x}{x}. Multiply \frac{x+4}{x\left(x-4\right)} times \frac{x+4}{x+4}.
\frac{-\frac{4\left(x+1\right)}{x^{2}+4x}}{\frac{9xx-\left(x+4\right)\left(x+4\right)}{x\left(x-4\right)\left(x+4\right)}}
Since \frac{9xx}{x\left(x-4\right)\left(x+4\right)} and \frac{\left(x+4\right)\left(x+4\right)}{x\left(x-4\right)\left(x+4\right)} have the same denominator, subtract them by subtracting their numerators.
\frac{-\frac{4\left(x+1\right)}{x^{2}+4x}}{\frac{9x^{2}-x^{2}-4x-4x-16}{x\left(x-4\right)\left(x+4\right)}}
Do the multiplications in 9xx-\left(x+4\right)\left(x+4\right).
\frac{-\frac{4\left(x+1\right)}{x^{2}+4x}}{\frac{8x^{2}-8x-16}{x\left(x-4\right)\left(x+4\right)}}
Combine like terms in 9x^{2}-x^{2}-4x-4x-16.
\frac{\left(-\frac{4\left(x+1\right)}{x^{2}+4x}\right)x\left(x-4\right)\left(x+4\right)}{8x^{2}-8x-16}
Divide -\frac{4\left(x+1\right)}{x^{2}+4x} by \frac{8x^{2}-8x-16}{x\left(x-4\right)\left(x+4\right)} by multiplying -\frac{4\left(x+1\right)}{x^{2}+4x} by the reciprocal of \frac{8x^{2}-8x-16}{x\left(x-4\right)\left(x+4\right)}.
\frac{\frac{-4\left(x+1\right)x}{x^{2}+4x}\left(x-4\right)\left(x+4\right)}{8x^{2}-8x-16}
Express \left(-\frac{4\left(x+1\right)}{x^{2}+4x}\right)x as a single fraction.
\frac{\frac{-4\left(x+1\right)x\left(x-4\right)}{x^{2}+4x}\left(x+4\right)}{8x^{2}-8x-16}
Express \frac{-4\left(x+1\right)x}{x^{2}+4x}\left(x-4\right) as a single fraction.
\frac{\frac{-4\left(x+1\right)x\left(x-4\right)\left(x+4\right)}{x^{2}+4x}}{8x^{2}-8x-16}
Express \frac{-4\left(x+1\right)x\left(x-4\right)}{x^{2}+4x}\left(x+4\right) as a single fraction.
\frac{-4\left(x+1\right)x\left(x-4\right)\left(x+4\right)}{\left(x^{2}+4x\right)\left(8x^{2}-8x-16\right)}
Express \frac{\frac{-4\left(x+1\right)x\left(x-4\right)\left(x+4\right)}{x^{2}+4x}}{8x^{2}-8x-16} as a single fraction.
\frac{-4x\left(x-4\right)\left(x+1\right)\left(x+4\right)}{8x\left(x-2\right)\left(x+1\right)\left(x+4\right)}
Factor the expressions that are not already factored.
\frac{-\left(x-4\right)}{2\left(x-2\right)}
Cancel out 4x\left(x+1\right)\left(x+4\right) in both numerator and denominator.
\frac{-x+4}{2x-4}
Expand the expression.