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Differentiate w.r.t. x
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-\frac{7}{3}\left(-\frac{4}{3}\right)x^{-\frac{7}{3}-1}
The derivative of ax^{n} is nax^{n-1}.
\frac{28}{9}x^{-\frac{7}{3}-1}
Multiply -\frac{7}{3} times -\frac{4}{3} by multiplying numerator times numerator and denominator times denominator. Then reduce the fraction to lowest terms if possible.
\frac{28}{9}x^{-\frac{10}{3}}
Subtract 1 from -\frac{7}{3}.