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-\frac{3}{8}x=-2
Subtract 2 from both sides. Anything subtracted from zero gives its negation.
x=-2\left(-\frac{8}{3}\right)
Multiply both sides by -\frac{8}{3}, the reciprocal of -\frac{3}{8}.
x=\frac{-2\left(-8\right)}{3}
Express -2\left(-\frac{8}{3}\right) as a single fraction.
x=\frac{16}{3}
Multiply -2 and -8 to get 16.