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-\frac{2m^{6}p^{2}q^{3}\left(-2\right)q^{-3}\left(-2\right)m^{-4}p^{4}q^{-3}}{\left(m^{0}p^{4}q^{2}\right)^{4}}
To multiply powers of the same base, add their exponents. Add 4 and 2 to get 6.
-\frac{2m^{2}p^{2}q^{3}\left(-2\right)q^{-3}\left(-2\right)p^{4}q^{-3}}{\left(m^{0}p^{4}q^{2}\right)^{4}}
To multiply powers of the same base, add their exponents. Add 6 and -4 to get 2.
-\frac{2m^{2}p^{6}q^{3}\left(-2\right)q^{-3}\left(-2\right)q^{-3}}{\left(m^{0}p^{4}q^{2}\right)^{4}}
To multiply powers of the same base, add their exponents. Add 2 and 4 to get 6.
-\frac{2m^{2}p^{6}\left(-2\right)\left(-2\right)q^{-3}}{\left(m^{0}p^{4}q^{2}\right)^{4}}
Multiply q^{3} and q^{-3} to get 1.
-\frac{-4m^{2}p^{6}\left(-2\right)q^{-3}}{\left(m^{0}p^{4}q^{2}\right)^{4}}
Multiply 2 and -2 to get -4.
-\frac{8m^{2}p^{6}q^{-3}}{\left(m^{0}p^{4}q^{2}\right)^{4}}
Multiply -4 and -2 to get 8.
-\frac{8m^{2}p^{6}q^{-3}}{\left(1p^{4}q^{2}\right)^{4}}
Calculate m to the power of 0 and get 1.
-\frac{8m^{2}p^{6}q^{-3}}{1^{4}\left(p^{4}\right)^{4}\left(q^{2}\right)^{4}}
Expand \left(1p^{4}q^{2}\right)^{4}.
-\frac{8m^{2}p^{6}q^{-3}}{1^{4}p^{16}\left(q^{2}\right)^{4}}
To raise a power to another power, multiply the exponents. Multiply 4 and 4 to get 16.
-\frac{8m^{2}p^{6}q^{-3}}{1^{4}p^{16}q^{8}}
To raise a power to another power, multiply the exponents. Multiply 2 and 4 to get 8.
-\frac{8m^{2}p^{6}q^{-3}}{1p^{16}q^{8}}
Calculate 1 to the power of 4 and get 1.
-\frac{8q^{-3}m^{2}}{q^{8}p^{10}}
Cancel out p^{6} in both numerator and denominator.
-\frac{8m^{2}}{p^{10}q^{11}}
To divide powers of the same base, subtract the numerator's exponent from the denominator's exponent.
-\frac{2m^{6}p^{2}q^{3}\left(-2\right)q^{-3}\left(-2\right)m^{-4}p^{4}q^{-3}}{\left(m^{0}p^{4}q^{2}\right)^{4}}
To multiply powers of the same base, add their exponents. Add 4 and 2 to get 6.
-\frac{2m^{2}p^{2}q^{3}\left(-2\right)q^{-3}\left(-2\right)p^{4}q^{-3}}{\left(m^{0}p^{4}q^{2}\right)^{4}}
To multiply powers of the same base, add their exponents. Add 6 and -4 to get 2.
-\frac{2m^{2}p^{6}q^{3}\left(-2\right)q^{-3}\left(-2\right)q^{-3}}{\left(m^{0}p^{4}q^{2}\right)^{4}}
To multiply powers of the same base, add their exponents. Add 2 and 4 to get 6.
-\frac{2m^{2}p^{6}\left(-2\right)\left(-2\right)q^{-3}}{\left(m^{0}p^{4}q^{2}\right)^{4}}
Multiply q^{3} and q^{-3} to get 1.
-\frac{-4m^{2}p^{6}\left(-2\right)q^{-3}}{\left(m^{0}p^{4}q^{2}\right)^{4}}
Multiply 2 and -2 to get -4.
-\frac{8m^{2}p^{6}q^{-3}}{\left(m^{0}p^{4}q^{2}\right)^{4}}
Multiply -4 and -2 to get 8.
-\frac{8m^{2}p^{6}q^{-3}}{\left(1p^{4}q^{2}\right)^{4}}
Calculate m to the power of 0 and get 1.
-\frac{8m^{2}p^{6}q^{-3}}{1^{4}\left(p^{4}\right)^{4}\left(q^{2}\right)^{4}}
Expand \left(1p^{4}q^{2}\right)^{4}.
-\frac{8m^{2}p^{6}q^{-3}}{1^{4}p^{16}\left(q^{2}\right)^{4}}
To raise a power to another power, multiply the exponents. Multiply 4 and 4 to get 16.
-\frac{8m^{2}p^{6}q^{-3}}{1^{4}p^{16}q^{8}}
To raise a power to another power, multiply the exponents. Multiply 2 and 4 to get 8.
-\frac{8m^{2}p^{6}q^{-3}}{1p^{16}q^{8}}
Calculate 1 to the power of 4 and get 1.
-\frac{8q^{-3}m^{2}}{q^{8}p^{10}}
Cancel out p^{6} in both numerator and denominator.
-\frac{8m^{2}}{p^{10}q^{11}}
To divide powers of the same base, subtract the numerator's exponent from the denominator's exponent.