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Differentiate w.r.t. a
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-2a^{1-1}+2\left(-4\right)a^{2-1}+3\left(-8\right)a^{3-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
-2a^{0}+2\left(-4\right)a^{2-1}+3\left(-8\right)a^{3-1}
Subtract 1 from 1.
-2a^{0}-8a^{2-1}+3\left(-8\right)a^{3-1}
Multiply 2 times -4.
-2a^{0}-8a^{1}+3\left(-8\right)a^{3-1}
Subtract 1 from 2.
-2a^{0}-8a^{1}-24a^{3-1}
Multiply 2 times -4.
-2a^{0}-8a^{1}-24a^{2}
Subtract 1 from 3.
-2a^{0}-8a-24a^{2}
For any term t, t^{1}=t.
-2-8a-24a^{2}
For any term t except 0, t^{0}=1.