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-81\times \frac{4}{9}\left(-\frac{4}{9}\right)\times \frac{1}{16}
Reduce the fraction \frac{100}{225} to lowest terms by extracting and canceling out 25.
\frac{-81\times 4}{9}\left(-\frac{4}{9}\right)\times \frac{1}{16}
Express -81\times \frac{4}{9} as a single fraction.
\frac{-324}{9}\left(-\frac{4}{9}\right)\times \frac{1}{16}
Multiply -81 and 4 to get -324.
-36\left(-\frac{4}{9}\right)\times \frac{1}{16}
Divide -324 by 9 to get -36.
\frac{-36\left(-4\right)}{9}\times \frac{1}{16}
Express -36\left(-\frac{4}{9}\right) as a single fraction.
\frac{144}{9}\times \frac{1}{16}
Multiply -36 and -4 to get 144.
16\times \frac{1}{16}
Divide 144 by 9 to get 16.
1
Cancel out 16 and 16.