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x^{2}-5xy+2x-5yx+25y^{2}-10y-4x+20y-8
Apply the distributive property by multiplying each term of x-5y-4 by each term of x-5y+2.
x^{2}-10xy+2x+25y^{2}-10y-4x+20y-8
Combine -5xy and -5yx to get -10xy.
x^{2}-10xy-2x+25y^{2}-10y+20y-8
Combine 2x and -4x to get -2x.
x^{2}-10xy-2x+25y^{2}+10y-8
Combine -10y and 20y to get 10y.
x^{2}-5xy+2x-5yx+25y^{2}-10y-4x+20y-8
Apply the distributive property by multiplying each term of x-5y-4 by each term of x-5y+2.
x^{2}-10xy+2x+25y^{2}-10y-4x+20y-8
Combine -5xy and -5yx to get -10xy.
x^{2}-10xy-2x+25y^{2}-10y+20y-8
Combine 2x and -4x to get -2x.
x^{2}-10xy-2x+25y^{2}+10y-8
Combine -10y and 20y to get 10y.