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x^{2}-8x+16-3\left(x-2\right)\left(x+1\right)
Use binomial theorem \left(a-b\right)^{2}=a^{2}-2ab+b^{2} to expand \left(x-4\right)^{2}.
x^{2}-8x+16+\left(-3x+6\right)\left(x+1\right)
Use the distributive property to multiply -3 by x-2.
x^{2}-8x+16-3x^{2}+3x+6
Use the distributive property to multiply -3x+6 by x+1 and combine like terms.
-2x^{2}-8x+16+3x+6
Combine x^{2} and -3x^{2} to get -2x^{2}.
-2x^{2}-5x+16+6
Combine -8x and 3x to get -5x.
-2x^{2}-5x+22
Add 16 and 6 to get 22.
x^{2}-8x+16-3\left(x-2\right)\left(x+1\right)
Use binomial theorem \left(a-b\right)^{2}=a^{2}-2ab+b^{2} to expand \left(x-4\right)^{2}.
x^{2}-8x+16+\left(-3x+6\right)\left(x+1\right)
Use the distributive property to multiply -3 by x-2.
x^{2}-8x+16-3x^{2}+3x+6
Use the distributive property to multiply -3x+6 by x+1 and combine like terms.
-2x^{2}-8x+16+3x+6
Combine x^{2} and -3x^{2} to get -2x^{2}.
-2x^{2}-5x+16+6
Combine -8x and 3x to get -5x.
-2x^{2}-5x+22
Add 16 and 6 to get 22.