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\left(x^{2}\right)^{2}+16x^{2}+64-81
Use binomial theorem \left(a+b\right)^{2}=a^{2}+2ab+b^{2} to expand \left(x^{2}+8\right)^{2}.
x^{4}+16x^{2}+64-81
To raise a power to another power, multiply the exponents. Multiply 2 and 2 to get 4.
x^{4}+16x^{2}-17
Subtract 81 from 64 to get -17.
\left(x^{2}\right)^{2}+16x^{2}+64-81
Use binomial theorem \left(a+b\right)^{2}=a^{2}+2ab+b^{2} to expand \left(x^{2}+8\right)^{2}.
x^{4}+16x^{2}+64-81
To raise a power to another power, multiply the exponents. Multiply 2 and 2 to get 4.
x^{4}+16x^{2}-17
Subtract 81 from 64 to get -17.