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\left(x^{2}\right)^{2}+8x^{2}x+16x^{2}+8\left(x^{2}+4x\right)+16
Use binomial theorem \left(a+b\right)^{2}=a^{2}+2ab+b^{2} to expand \left(x^{2}+4x\right)^{2}.
x^{4}+8x^{2}x+16x^{2}+8\left(x^{2}+4x\right)+16
To raise a power to another power, multiply the exponents. Multiply 2 and 2 to get 4.
x^{4}+8x^{3}+16x^{2}+8\left(x^{2}+4x\right)+16
To multiply powers of the same base, add their exponents. Add 2 and 1 to get 3.
x^{4}+8x^{3}+16x^{2}+8x^{2}+32x+16
Use the distributive property to multiply 8 by x^{2}+4x.
x^{4}+8x^{3}+24x^{2}+32x+16
Combine 16x^{2} and 8x^{2} to get 24x^{2}.
\left(x^{2}\right)^{2}+8x^{2}x+16x^{2}+8\left(x^{2}+4x\right)+16
Use binomial theorem \left(a+b\right)^{2}=a^{2}+2ab+b^{2} to expand \left(x^{2}+4x\right)^{2}.
x^{4}+8x^{2}x+16x^{2}+8\left(x^{2}+4x\right)+16
To raise a power to another power, multiply the exponents. Multiply 2 and 2 to get 4.
x^{4}+8x^{3}+16x^{2}+8\left(x^{2}+4x\right)+16
To multiply powers of the same base, add their exponents. Add 2 and 1 to get 3.
x^{4}+8x^{3}+16x^{2}+8x^{2}+32x+16
Use the distributive property to multiply 8 by x^{2}+4x.
x^{4}+8x^{3}+24x^{2}+32x+16
Combine 16x^{2} and 8x^{2} to get 24x^{2}.