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x^{2}-5xy+9x+5yx-25y^{2}+45y-9x+45y-81
Apply the distributive property by multiplying each term of x+5y-9 by each term of x-5y+9.
x^{2}+9x-25y^{2}+45y-9x+45y-81
Combine -5xy and 5yx to get 0.
x^{2}-25y^{2}+45y+45y-81
Combine 9x and -9x to get 0.
x^{2}-25y^{2}+90y-81
Combine 45y and 45y to get 90y.
x^{2}-5xy+9x+5yx-25y^{2}+45y-9x+45y-81
Apply the distributive property by multiplying each term of x+5y-9 by each term of x-5y+9.
x^{2}+9x-25y^{2}+45y-9x+45y-81
Combine -5xy and 5yx to get 0.
x^{2}-25y^{2}+45y+45y-81
Combine 9x and -9x to get 0.
x^{2}-25y^{2}+90y-81
Combine 45y and 45y to get 90y.