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\left(x^{2}-16y^{2}\right)\left(x^{2}+16y^{2}\right)
Use the distributive property to multiply x+4y by x-4y and combine like terms.
\left(x^{2}\right)^{2}-\left(16y^{2}\right)^{2}
Multiplication can be transformed into difference of squares using the rule: \left(a-b\right)\left(a+b\right)=a^{2}-b^{2}.
x^{4}-\left(16y^{2}\right)^{2}
To raise a power to another power, multiply the exponents. Multiply 2 and 2 to get 4.
x^{4}-16^{2}\left(y^{2}\right)^{2}
Expand \left(16y^{2}\right)^{2}.
x^{4}-16^{2}y^{4}
To raise a power to another power, multiply the exponents. Multiply 2 and 2 to get 4.
x^{4}-256y^{4}
Calculate 16 to the power of 2 and get 256.
\left(x^{2}-16y^{2}\right)\left(x^{2}+16y^{2}\right)
Use the distributive property to multiply x+4y by x-4y and combine like terms.
\left(x^{2}\right)^{2}-\left(16y^{2}\right)^{2}
Multiplication can be transformed into difference of squares using the rule: \left(a-b\right)\left(a+b\right)=a^{2}-b^{2}.
x^{4}-\left(16y^{2}\right)^{2}
To raise a power to another power, multiply the exponents. Multiply 2 and 2 to get 4.
x^{4}-16^{2}\left(y^{2}\right)^{2}
Expand \left(16y^{2}\right)^{2}.
x^{4}-16^{2}y^{4}
To raise a power to another power, multiply the exponents. Multiply 2 and 2 to get 4.
x^{4}-256y^{4}
Calculate 16 to the power of 2 and get 256.