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\left(x+3\right)\left(x^{2}-8x+16\right)-x^{3}
Use binomial theorem \left(a-b\right)^{2}=a^{2}-2ab+b^{2} to expand \left(x-4\right)^{2}.
x^{3}-5x^{2}-8x+48-x^{3}
Use the distributive property to multiply x+3 by x^{2}-8x+16 and combine like terms.
-5x^{2}-8x+48
Combine x^{3} and -x^{3} to get 0.
\left(x+3\right)\left(x^{2}-8x+16\right)-x^{3}
Use binomial theorem \left(a-b\right)^{2}=a^{2}-2ab+b^{2} to expand \left(x-4\right)^{2}.
x^{3}-5x^{2}-8x+48-x^{3}
Use the distributive property to multiply x+3 by x^{2}-8x+16 and combine like terms.
-5x^{2}-8x+48
Combine x^{3} and -x^{3} to get 0.