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Differentiate w.r.t. u
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\left(u^{-5}\right)^{7}
Use the rules of exponents to simplify the expression.
u^{-5\times 7}
To raise a power to another power, multiply the exponents.
\frac{1}{u^{35}}
Multiply -5 times 7.
7\left(u^{-5}\right)^{7-1}\frac{\mathrm{d}}{\mathrm{d}u}(u^{-5})
If F is the composition of two differentiable functions f\left(u\right) and u=g\left(x\right), that is, if F\left(x\right)=f\left(g\left(x\right)\right), then the derivative of F is the derivative of f with respect to u times the derivative of g with respect to x, that is, \frac{\mathrm{d}}{\mathrm{d}x}(F)\left(x\right)=\frac{\mathrm{d}}{\mathrm{d}x}(f)\left(g\left(x\right)\right)\frac{\mathrm{d}}{\mathrm{d}x}(g)\left(x\right).
7\left(u^{-5}\right)^{6}\left(-5\right)u^{-5-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
-35u^{-6}\left(u^{-5}\right)^{6}
Simplify.