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Differentiate w.r.t. n
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\left(n^{5}\right)^{-9}
Use the rules of exponents to simplify the expression.
n^{5\left(-9\right)}
To raise a power to another power, multiply the exponents.
\frac{1}{n^{45}}
Multiply 5 times -9.
-9\left(n^{5}\right)^{-9-1}\frac{\mathrm{d}}{\mathrm{d}n}(n^{5})
If F is the composition of two differentiable functions f\left(u\right) and u=g\left(x\right), that is, if F\left(x\right)=f\left(g\left(x\right)\right), then the derivative of F is the derivative of f with respect to u times the derivative of g with respect to x, that is, \frac{\mathrm{d}}{\mathrm{d}x}(F)\left(x\right)=\frac{\mathrm{d}}{\mathrm{d}x}(f)\left(g\left(x\right)\right)\frac{\mathrm{d}}{\mathrm{d}x}(g)\left(x\right).
-9\left(n^{5}\right)^{-10}\times 5n^{5-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
-45n^{4}\left(n^{5}\right)^{-10}
Simplify.