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m^{2}+2mn+n^{2}-\left(2m+n\right)^{2}+\left(m-9n\right)^{2}
Use binomial theorem \left(a+b\right)^{2}=a^{2}+2ab+b^{2} to expand \left(m+n\right)^{2}.
m^{2}+2mn+n^{2}-\left(4m^{2}+4mn+n^{2}\right)+\left(m-9n\right)^{2}
Use binomial theorem \left(a+b\right)^{2}=a^{2}+2ab+b^{2} to expand \left(2m+n\right)^{2}.
m^{2}+2mn+n^{2}-4m^{2}-4mn-n^{2}+\left(m-9n\right)^{2}
To find the opposite of 4m^{2}+4mn+n^{2}, find the opposite of each term.
-3m^{2}+2mn+n^{2}-4mn-n^{2}+\left(m-9n\right)^{2}
Combine m^{2} and -4m^{2} to get -3m^{2}.
-3m^{2}-2mn+n^{2}-n^{2}+\left(m-9n\right)^{2}
Combine 2mn and -4mn to get -2mn.
-3m^{2}-2mn+\left(m-9n\right)^{2}
Combine n^{2} and -n^{2} to get 0.
-3m^{2}-2mn+m^{2}-18mn+81n^{2}
Use binomial theorem \left(a-b\right)^{2}=a^{2}-2ab+b^{2} to expand \left(m-9n\right)^{2}.
-2m^{2}-2mn-18mn+81n^{2}
Combine -3m^{2} and m^{2} to get -2m^{2}.
-2m^{2}-20mn+81n^{2}
Combine -2mn and -18mn to get -20mn.
m^{2}+2mn+n^{2}-\left(2m+n\right)^{2}+\left(m-9n\right)^{2}
Use binomial theorem \left(a+b\right)^{2}=a^{2}+2ab+b^{2} to expand \left(m+n\right)^{2}.
m^{2}+2mn+n^{2}-\left(4m^{2}+4mn+n^{2}\right)+\left(m-9n\right)^{2}
Use binomial theorem \left(a+b\right)^{2}=a^{2}+2ab+b^{2} to expand \left(2m+n\right)^{2}.
m^{2}+2mn+n^{2}-4m^{2}-4mn-n^{2}+\left(m-9n\right)^{2}
To find the opposite of 4m^{2}+4mn+n^{2}, find the opposite of each term.
-3m^{2}+2mn+n^{2}-4mn-n^{2}+\left(m-9n\right)^{2}
Combine m^{2} and -4m^{2} to get -3m^{2}.
-3m^{2}-2mn+n^{2}-n^{2}+\left(m-9n\right)^{2}
Combine 2mn and -4mn to get -2mn.
-3m^{2}-2mn+\left(m-9n\right)^{2}
Combine n^{2} and -n^{2} to get 0.
-3m^{2}-2mn+m^{2}-18mn+81n^{2}
Use binomial theorem \left(a-b\right)^{2}=a^{2}-2ab+b^{2} to expand \left(m-9n\right)^{2}.
-2m^{2}-2mn-18mn+81n^{2}
Combine -3m^{2} and m^{2} to get -2m^{2}.
-2m^{2}-20mn+81n^{2}
Combine -2mn and -18mn to get -20mn.