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Differentiate w.r.t. c
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\frac{\frac{a^{2}b^{2}c^{3}}{\frac{a^{\frac{2}{3}}b^{\frac{2}{3}}}{3}}c^{-1}}{-2c^{2}+bc}
Expand \left(ab\right)^{2}.
\frac{\frac{a^{2}b^{2}c^{3}\times 3}{a^{\frac{2}{3}}b^{\frac{2}{3}}}c^{-1}}{-2c^{2}+bc}
Divide a^{2}b^{2}c^{3} by \frac{a^{\frac{2}{3}}b^{\frac{2}{3}}}{3} by multiplying a^{2}b^{2}c^{3} by the reciprocal of \frac{a^{\frac{2}{3}}b^{\frac{2}{3}}}{3}.
\frac{3a^{\frac{4}{3}}b^{\frac{4}{3}}c^{3}c^{-1}}{-2c^{2}+bc}
Cancel out a^{\frac{2}{3}}b^{\frac{2}{3}} in both numerator and denominator.
\frac{3a^{\frac{4}{3}}b^{\frac{4}{3}}c^{2}}{-2c^{2}+bc}
To multiply powers of the same base, add their exponents. Add 3 and -1 to get 2.
\frac{3a^{\frac{4}{3}}b^{\frac{4}{3}}c^{2}}{c\left(b-2c\right)}
Factor the expressions that are not already factored.
\frac{3ca^{\frac{4}{3}}b^{\frac{4}{3}}}{b-2c}
Cancel out c in both numerator and denominator.