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Differentiate w.r.t. a
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a^{2}\left(-3\right)a^{2}
Multiply a and a to get a^{2}.
a^{4}\left(-3\right)
To multiply powers of the same base, add their exponents. Add 2 and 2 to get 4.
\frac{\mathrm{d}}{\mathrm{d}a}(a^{2}\left(-3\right)a^{2})
Multiply a and a to get a^{2}.
\frac{\mathrm{d}}{\mathrm{d}a}(a^{4}\left(-3\right))
To multiply powers of the same base, add their exponents. Add 2 and 2 to get 4.
4\left(-3\right)a^{4-1}
The derivative of ax^{n} is nax^{n-1}.
-12a^{4-1}
Multiply 4 times -3.
-12a^{3}
Subtract 1 from 4.