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Evaluate
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Differentiate w.r.t. x
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8x^{16}\left(-3\right)\times 5x^{6}
To multiply powers of the same base, add their exponents. Add 7 and 9 to get 16.
8x^{22}\left(-3\right)\times 5
To multiply powers of the same base, add their exponents. Add 16 and 6 to get 22.
-24x^{22}\times 5
Multiply 8 and -3 to get -24.
-120x^{22}
Multiply -24 and 5 to get -120.
\frac{\mathrm{d}}{\mathrm{d}x}(8x^{16}\left(-3\right)\times 5x^{6})
To multiply powers of the same base, add their exponents. Add 7 and 9 to get 16.
\frac{\mathrm{d}}{\mathrm{d}x}(8x^{22}\left(-3\right)\times 5)
To multiply powers of the same base, add their exponents. Add 16 and 6 to get 22.
\frac{\mathrm{d}}{\mathrm{d}x}(-24x^{22}\times 5)
Multiply 8 and -3 to get -24.
\frac{\mathrm{d}}{\mathrm{d}x}(-120x^{22})
Multiply -24 and 5 to get -120.
22\left(-120\right)x^{22-1}
The derivative of ax^{n} is nax^{n-1}.
-2640x^{22-1}
Multiply 22 times -120.
-2640x^{21}
Subtract 1 from 22.