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Differentiate w.r.t. x
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64^{\frac{5}{6}}\left(x^{4}\right)^{\frac{5}{6}}
Expand \left(64x^{4}\right)^{\frac{5}{6}}.
64^{\frac{5}{6}}x^{\frac{10}{3}}
To raise a power to another power, multiply the exponents. Multiply 4 and \frac{5}{6} to get \frac{10}{3}.
32x^{\frac{10}{3}}
Calculate 64 to the power of \frac{5}{6} and get 32.
\frac{5}{6}\times \left(64x^{4}\right)^{\frac{5}{6}-1}\frac{\mathrm{d}}{\mathrm{d}x}(64x^{4})
If F is the composition of two differentiable functions f\left(u\right) and u=g\left(x\right), that is, if F\left(x\right)=f\left(g\left(x\right)\right), then the derivative of F is the derivative of f with respect to u times the derivative of g with respect to x, that is, \frac{\mathrm{d}}{\mathrm{d}x}(F)\left(x\right)=\frac{\mathrm{d}}{\mathrm{d}x}(f)\left(g\left(x\right)\right)\frac{\mathrm{d}}{\mathrm{d}x}(g)\left(x\right).
\frac{5}{6}\times \left(64x^{4}\right)^{-\frac{1}{6}}\times 4\times 64x^{4-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
\frac{640}{3}x^{3}\times \left(64x^{4}\right)^{-\frac{1}{6}}
Simplify.