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Differentiate w.r.t. x
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\frac{\mathrm{d}}{\mathrm{d}x}(-160x^{2})
Multiply 4 and -40 to get -160.
2\left(-160\right)x^{2-1}
The derivative of ax^{n} is nax^{n-1}.
-320x^{2-1}
Multiply 2 times -160.
-320x^{1}
Subtract 1 from 2.
-320x
For any term t, t^{1}=t.
-160x^{2}
Multiply 4 and -40 to get -160.