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Differentiate w.r.t. x
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3^{1}x^{-6}q^{3}\left(-5\right)^{1}x^{2}q^{-6}
Use the rules of exponents to simplify the expression.
3^{1}\left(-5\right)^{1}x^{-6}x^{2}q^{3}q^{-6}
Use the Commutative Property of Multiplication.
3^{1}\left(-5\right)^{1}x^{-6+2}q^{3-6}
To multiply powers of the same base, add their exponents.
3^{1}\left(-5\right)^{1}x^{-4}q^{3-6}
Add the exponents -6 and 2.
3^{1}\left(-5\right)^{1}\times \frac{1}{x^{4}}q^{-3}
Add the exponents 3 and -6.
-15\times \frac{1}{x^{4}}\times \frac{1}{q^{3}}
Multiply 3 times -5.