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2^{2}\left(x^{2}\right)^{2}\left(-3y\right)^{3}\left(-5xz\right)^{3}
Expand \left(2x^{2}\right)^{2}.
2^{2}x^{4}\left(-3y\right)^{3}\left(-5xz\right)^{3}
To raise a power to another power, multiply the exponents. Multiply 2 and 2 to get 4.
4x^{4}\left(-3y\right)^{3}\left(-5xz\right)^{3}
Calculate 2 to the power of 2 and get 4.
4x^{4}\left(-3\right)^{3}y^{3}\left(-5xz\right)^{3}
Expand \left(-3y\right)^{3}.
4x^{4}\left(-27\right)y^{3}\left(-5xz\right)^{3}
Calculate -3 to the power of 3 and get -27.
-108x^{4}y^{3}\left(-5xz\right)^{3}
Multiply 4 and -27 to get -108.
-108x^{4}y^{3}\left(-5\right)^{3}x^{3}z^{3}
Expand \left(-5xz\right)^{3}.
-108x^{4}y^{3}\left(-125\right)x^{3}z^{3}
Calculate -5 to the power of 3 and get -125.
13500x^{4}y^{3}x^{3}z^{3}
Multiply -108 and -125 to get 13500.
13500x^{7}y^{3}z^{3}
To multiply powers of the same base, add their exponents. Add 4 and 3 to get 7.
2^{2}\left(x^{2}\right)^{2}\left(-3y\right)^{3}\left(-5xz\right)^{3}
Expand \left(2x^{2}\right)^{2}.
2^{2}x^{4}\left(-3y\right)^{3}\left(-5xz\right)^{3}
To raise a power to another power, multiply the exponents. Multiply 2 and 2 to get 4.
4x^{4}\left(-3y\right)^{3}\left(-5xz\right)^{3}
Calculate 2 to the power of 2 and get 4.
4x^{4}\left(-3\right)^{3}y^{3}\left(-5xz\right)^{3}
Expand \left(-3y\right)^{3}.
4x^{4}\left(-27\right)y^{3}\left(-5xz\right)^{3}
Calculate -3 to the power of 3 and get -27.
-108x^{4}y^{3}\left(-5xz\right)^{3}
Multiply 4 and -27 to get -108.
-108x^{4}y^{3}\left(-5\right)^{3}x^{3}z^{3}
Expand \left(-5xz\right)^{3}.
-108x^{4}y^{3}\left(-125\right)x^{3}z^{3}
Calculate -5 to the power of 3 and get -125.
13500x^{4}y^{3}x^{3}z^{3}
Multiply -108 and -125 to get 13500.
13500x^{7}y^{3}z^{3}
To multiply powers of the same base, add their exponents. Add 4 and 3 to get 7.