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4x^{2}+20x+25-\left(5x-3\right)^{2}
Use binomial theorem \left(a+b\right)^{2}=a^{2}+2ab+b^{2} to expand \left(2x+5\right)^{2}.
4x^{2}+20x+25-\left(25x^{2}-30x+9\right)
Use binomial theorem \left(a-b\right)^{2}=a^{2}-2ab+b^{2} to expand \left(5x-3\right)^{2}.
4x^{2}+20x+25-25x^{2}+30x-9
To find the opposite of 25x^{2}-30x+9, find the opposite of each term.
-21x^{2}+20x+25+30x-9
Combine 4x^{2} and -25x^{2} to get -21x^{2}.
-21x^{2}+50x+25-9
Combine 20x and 30x to get 50x.
-21x^{2}+50x+16
Subtract 9 from 25 to get 16.
4x^{2}+20x+25-\left(5x-3\right)^{2}
Use binomial theorem \left(a+b\right)^{2}=a^{2}+2ab+b^{2} to expand \left(2x+5\right)^{2}.
4x^{2}+20x+25-\left(25x^{2}-30x+9\right)
Use binomial theorem \left(a-b\right)^{2}=a^{2}-2ab+b^{2} to expand \left(5x-3\right)^{2}.
4x^{2}+20x+25-25x^{2}+30x-9
To find the opposite of 25x^{2}-30x+9, find the opposite of each term.
-21x^{2}+20x+25+30x-9
Combine 4x^{2} and -25x^{2} to get -21x^{2}.
-21x^{2}+50x+25-9
Combine 20x and 30x to get 50x.
-21x^{2}+50x+16
Subtract 9 from 25 to get 16.