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Differentiate w.r.t. a_5
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2a_{5}+6\left(\frac{6\times 125}{96}-2746\right)
Multiply 3 and 2 to get 6.
2a_{5}+6\left(\frac{750}{96}-2746\right)
Multiply 6 and 125 to get 750.
2a_{5}+6\left(\frac{125}{16}-2746\right)
Reduce the fraction \frac{750}{96} to lowest terms by extracting and canceling out 6.
2a_{5}+6\left(\frac{125}{16}-\frac{43936}{16}\right)
Convert 2746 to fraction \frac{43936}{16}.
2a_{5}+6\times \frac{125-43936}{16}
Since \frac{125}{16} and \frac{43936}{16} have the same denominator, subtract them by subtracting their numerators.
2a_{5}+6\left(-\frac{43811}{16}\right)
Subtract 43936 from 125 to get -43811.
2a_{5}+\frac{6\left(-43811\right)}{16}
Express 6\left(-\frac{43811}{16}\right) as a single fraction.
2a_{5}+\frac{-262866}{16}
Multiply 6 and -43811 to get -262866.
2a_{5}+-\frac{131433}{8}
Reduce the fraction \frac{-262866}{16} to lowest terms by extracting and canceling out 2.