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4a^{2}-12ab+9b^{2}-3\left(a+4b\right)\left(a-4b\right)
Use binomial theorem \left(p-q\right)^{2}=p^{2}-2pq+q^{2} to expand \left(2a-3b\right)^{2}.
4a^{2}-12ab+9b^{2}+\left(-3a-12b\right)\left(a-4b\right)
Use the distributive property to multiply -3 by a+4b.
4a^{2}-12ab+9b^{2}-3a^{2}+48b^{2}
Use the distributive property to multiply -3a-12b by a-4b and combine like terms.
a^{2}-12ab+9b^{2}+48b^{2}
Combine 4a^{2} and -3a^{2} to get a^{2}.
a^{2}-12ab+57b^{2}
Combine 9b^{2} and 48b^{2} to get 57b^{2}.
4a^{2}-12ab+9b^{2}-3\left(a+4b\right)\left(a-4b\right)
Use binomial theorem \left(p-q\right)^{2}=p^{2}-2pq+q^{2} to expand \left(2a-3b\right)^{2}.
4a^{2}-12ab+9b^{2}+\left(-3a-12b\right)\left(a-4b\right)
Use the distributive property to multiply -3 by a+4b.
4a^{2}-12ab+9b^{2}-3a^{2}+48b^{2}
Use the distributive property to multiply -3a-12b by a-4b and combine like terms.
a^{2}-12ab+9b^{2}+48b^{2}
Combine 4a^{2} and -3a^{2} to get a^{2}.
a^{2}-12ab+57b^{2}
Combine 9b^{2} and 48b^{2} to get 57b^{2}.