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Differentiate w.r.t. a
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2^{1}a^{2}b^{3}\times 6^{1}a^{-3}b^{-5}
Use the rules of exponents to simplify the expression.
2^{1}\times 6^{1}a^{2}a^{-3}b^{3}b^{-5}
Use the Commutative Property of Multiplication.
2^{1}\times 6^{1}a^{2-3}b^{3-5}
To multiply powers of the same base, add their exponents.
2^{1}\times 6^{1}\times \frac{1}{a}b^{3-5}
Add the exponents 2 and -3.
2^{1}\times 6^{1}\times \frac{1}{a}b^{-2}
Add the exponents 3 and -5.
12\times \frac{1}{a}\times \frac{1}{b^{2}}
Multiply 2 times 6.