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Evaluate
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Differentiate w.r.t. x
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\left(-y^{5}\right)z^{2}\left(-2\right)x^{3}\left(-3\right)xy^{4}
Multiply z and z to get z^{2}.
\left(-y^{5}\right)z^{2}\left(-2\right)x^{4}\left(-3\right)y^{4}
To multiply powers of the same base, add their exponents. Add 3 and 1 to get 4.
\left(-y^{5}\right)z^{2}\times 6x^{4}y^{4}
Multiply -2 and -3 to get 6.
-6y^{5}z^{2}x^{4}y^{4}
Multiply -1 and 6 to get -6.
-6y^{9}z^{2}x^{4}
To multiply powers of the same base, add their exponents. Add 5 and 4 to get 9.