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\left(-b\right)b-4\left(-b\right)a^{2}-4a^{2}b+16a^{4}
Use the distributive property to multiply -b-4a^{2} by b-4a^{2}.
\left(-b\right)b+4ba^{2}-4a^{2}b+16a^{4}
Multiply -4 and -1 to get 4.
\left(-b\right)b+16a^{4}
Combine 4ba^{2} and -4a^{2}b to get 0.
-b^{2}+16a^{4}
Multiply b and b to get b^{2}.
\left(-b\right)b-4\left(-b\right)a^{2}-4a^{2}b+16a^{4}
Use the distributive property to multiply -b-4a^{2} by b-4a^{2}.
\left(-b\right)b+4ba^{2}-4a^{2}b+16a^{4}
Multiply -4 and -1 to get 4.
\left(-b\right)b+16a^{4}
Combine 4ba^{2} and -4a^{2}b to get 0.
-b^{2}+16a^{4}
Multiply b and b to get b^{2}.