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-64x^{3}-144x^{2}-108x-27
Use binomial theorem \left(a-b\right)^{3}=a^{3}-3a^{2}b+3ab^{2}-b^{3} to expand \left(-4x-3\right)^{3}.
-64x^{3}-144x^{2}-108x-27
Use binomial theorem \left(a-b\right)^{3}=a^{3}-3a^{2}b+3ab^{2}-b^{3} to expand \left(-4x-3\right)^{3}.