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Differentiate w.r.t. a
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\frac{\left(-4\right)^{1}a^{2}b^{3}}{\left(-\frac{8}{5}\right)^{1}a^{3}b^{1}}
Use the rules of exponents to simplify the expression.
\frac{\left(-4\right)^{1}}{\left(-\frac{8}{5}\right)^{1}}a^{2-3}b^{3-1}
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{\left(-4\right)^{1}}{\left(-\frac{8}{5}\right)^{1}}\times \frac{1}{a}b^{3-1}
Subtract 3 from 2.
\frac{\left(-4\right)^{1}}{\left(-\frac{8}{5}\right)^{1}}\times \frac{1}{a}b^{2}
Subtract 1 from 3.
\frac{5}{2}\times \frac{1}{a}b^{2}
Divide -4 by -\frac{8}{5} by multiplying -4 by the reciprocal of -\frac{8}{5}.
\frac{\mathrm{d}}{\mathrm{d}a}(\left(-\frac{4b^{3}}{-\frac{8b}{5}}\right)a^{2-3})
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{\mathrm{d}}{\mathrm{d}a}(\frac{5b^{2}}{2}\times \frac{1}{a})
Do the arithmetic.
-\frac{5b^{2}}{2}a^{-1-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
\left(-\frac{5b^{2}}{2}\right)a^{-2}
Do the arithmetic.