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Differentiate w.r.t. x
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-3x^{2}y^{3}\times \left(\frac{1}{y^{4}x^{6}}\right)^{-1}
To divide powers of the same base, subtract the numerator's exponent from the denominator's exponent.
-3x^{2}y^{3}\times \frac{1^{-1}}{\left(y^{4}x^{6}\right)^{-1}}
To raise \frac{1}{y^{4}x^{6}} to a power, raise both numerator and denominator to the power and then divide.
\frac{-3\times 1^{-1}}{\left(y^{4}x^{6}\right)^{-1}}x^{2}y^{3}
Express -3\times \frac{1^{-1}}{\left(y^{4}x^{6}\right)^{-1}} as a single fraction.
\frac{-3}{\left(y^{4}x^{6}\right)^{-1}}x^{2}y^{3}
Calculate 1 to the power of -1 and get 1.
\frac{-3}{\left(y^{4}\right)^{-1}\left(x^{6}\right)^{-1}}x^{2}y^{3}
Expand \left(y^{4}x^{6}\right)^{-1}.
\frac{-3}{y^{-4}\left(x^{6}\right)^{-1}}x^{2}y^{3}
To raise a power to another power, multiply the exponents. Multiply 4 and -1 to get -4.
\frac{-3}{y^{-4}x^{-6}}x^{2}y^{3}
To raise a power to another power, multiply the exponents. Multiply 6 and -1 to get -6.
\frac{-3x^{2}}{y^{-4}x^{-6}}y^{3}
Express \frac{-3}{y^{-4}x^{-6}}x^{2} as a single fraction.
\frac{-3x^{8}}{y^{-4}}y^{3}
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{-3x^{8}y^{3}}{y^{-4}}
Express \frac{-3x^{8}}{y^{-4}}y^{3} as a single fraction.
-3y^{7}x^{8}
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.