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Differentiate w.r.t. x
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-3x^{28}y^{15}\left(-3\right)y^{18}-29x^{12}y^{16}\times 4x^{16}y^{17}
To multiply powers of the same base, add their exponents. Add 13 and 15 to get 28.
-3x^{28}y^{33}\left(-3\right)-29x^{12}y^{16}\times 4x^{16}y^{17}
To multiply powers of the same base, add their exponents. Add 15 and 18 to get 33.
-3x^{28}y^{33}\left(-3\right)-29x^{28}y^{16}\times 4y^{17}
To multiply powers of the same base, add their exponents. Add 12 and 16 to get 28.
-3x^{28}y^{33}\left(-3\right)-29x^{28}y^{33}\times 4
To multiply powers of the same base, add their exponents. Add 16 and 17 to get 33.
9x^{28}y^{33}-29x^{28}y^{33}\times 4
Multiply -3 and -3 to get 9.
9x^{28}y^{33}-116x^{28}y^{33}
Multiply -29 and 4 to get -116.
-107x^{28}y^{33}
Combine 9x^{28}y^{33} and -116x^{28}y^{33} to get -107x^{28}y^{33}.
13\times 9x^{15}y^{33}x^{13-1}+12\left(-116x^{16}y^{33}\right)x^{12-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
117x^{15}y^{33}x^{13-1}+12\left(-116x^{16}y^{33}\right)x^{12-1}
Multiply 13 times -3\left(-3\right)y^{15}x^{15}y^{18}.
117x^{15}y^{33}x^{12}+12\left(-116x^{16}y^{33}\right)x^{12-1}
Subtract 1 from 13.
117x^{15}y^{33}x^{12}+\left(-1392x^{16}y^{33}\right)x^{12-1}
Multiply 12 times -29\times 4y^{16}x^{16}y^{17}.
117x^{15}y^{33}x^{12}+\left(-1392x^{16}y^{33}\right)x^{11}
Subtract 1 from 12.