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-2x\left(-x\right)+8x+4\left(-x\right)-16
Apply the distributive property by multiplying each term of -2x+4 by each term of -x-4.
2xx+8x+4\left(-x\right)-16
Multiply -2 and -1 to get 2.
2x^{2}+8x+4\left(-x\right)-16
Multiply x and x to get x^{2}.
2x^{2}+8x-4x-16
Multiply 4 and -1 to get -4.
2x^{2}+4x-16
Combine 8x and -4x to get 4x.
-2x\left(-x\right)+8x+4\left(-x\right)-16
Apply the distributive property by multiplying each term of -2x+4 by each term of -x-4.
2xx+8x+4\left(-x\right)-16
Multiply -2 and -1 to get 2.
2x^{2}+8x+4\left(-x\right)-16
Multiply x and x to get x^{2}.
2x^{2}+8x-4x-16
Multiply 4 and -1 to get -4.
2x^{2}+4x-16
Combine 8x and -4x to get 4x.