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\left(-2\right)^{4}-2^{6}\left(3-5\right)^{2}+\frac{\left(-4\right)^{2}}{-2^{2}}-\left(-1^{4}\right)
To raise a power to another power, multiply the exponents. Multiply 2 and 3 to get 6.
16-2^{6}\left(3-5\right)^{2}+\frac{\left(-4\right)^{2}}{-2^{2}}-\left(-1^{4}\right)
Calculate -2 to the power of 4 and get 16.
16-64\left(3-5\right)^{2}+\frac{\left(-4\right)^{2}}{-2^{2}}-\left(-1^{4}\right)
Calculate 2 to the power of 6 and get 64.
16-64\left(-2\right)^{2}+\frac{\left(-4\right)^{2}}{-2^{2}}-\left(-1^{4}\right)
Subtract 5 from 3 to get -2.
16-64\times 4+\frac{\left(-4\right)^{2}}{-2^{2}}-\left(-1^{4}\right)
Calculate -2 to the power of 2 and get 4.
16-256+\frac{\left(-4\right)^{2}}{-2^{2}}-\left(-1^{4}\right)
Multiply 64 and 4 to get 256.
-240+\frac{\left(-4\right)^{2}}{-2^{2}}-\left(-1^{4}\right)
Subtract 256 from 16 to get -240.
-240+\frac{16}{-2^{2}}-\left(-1^{4}\right)
Calculate -4 to the power of 2 and get 16.
-240+\frac{16}{-4}-\left(-1^{4}\right)
Calculate 2 to the power of 2 and get 4.
-240-4-\left(-1^{4}\right)
Divide 16 by -4 to get -4.
-244-\left(-1^{4}\right)
Subtract 4 from -240 to get -244.
-244-\left(-1\right)
Calculate 1 to the power of 4 and get 1.
-244+1
The opposite of -1 is 1.
-243
Add -244 and 1 to get -243.