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Differentiate w.r.t. b
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\frac{-12a^{4}b^{3}}{-3ab^{2}}-\frac{-45a^{3}b^{2}}{-9b}+7a^{3}\left(-2\right)b
To multiply powers of the same base, add their exponents. Add 1 and 2 to get 3.
\frac{-4ba^{3}}{-1}-\frac{-45a^{3}b^{2}}{-9b}+7a^{3}\left(-2\right)b
Cancel out 3ab^{2} in both numerator and denominator.
4ba^{3}-\frac{-45a^{3}b^{2}}{-9b}+7a^{3}\left(-2\right)b
Anything divided by -1 gives its opposite.
4ba^{3}-\frac{-5ba^{3}}{-1}+7a^{3}\left(-2\right)b
Cancel out 9b in both numerator and denominator.
4ba^{3}-5ba^{3}+7a^{3}\left(-2\right)b
Anything divided by -1 gives its opposite.
4ba^{3}-5ba^{3}-14a^{3}b
Multiply 7 and -2 to get -14.
-10ba^{3}-5ba^{3}
Combine 4ba^{3} and -14a^{3}b to get -10ba^{3}.
-15ba^{3}
Combine -10ba^{3} and -5ba^{3} to get -15ba^{3}.