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Differentiate w.r.t. p
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-\frac{3}{5}m^{5}n\left(-\frac{5}{3}\right)np
To multiply powers of the same base, add their exponents. Add 1 and 4 to get 5.
-\frac{3}{5}m^{5}n^{2}\left(-\frac{5}{3}\right)p
Multiply n and n to get n^{2}.
m^{5}n^{2}p
Multiply -\frac{3}{5} and -\frac{5}{3} to get 1.