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Differentiate w.r.t. x
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\left(\sqrt{4-4x+x^{2}+25}\right)^{2}
Use binomial theorem \left(a-b\right)^{2}=a^{2}-2ab+b^{2} to expand \left(2-x\right)^{2}.
\left(\sqrt{29-4x+x^{2}}\right)^{2}
Add 4 and 25 to get 29.
29-4x+x^{2}
Calculate \sqrt{29-4x+x^{2}} to the power of 2 and get 29-4x+x^{2}.
\frac{\mathrm{d}}{\mathrm{d}x}(\left(\sqrt{4-4x+x^{2}+25}\right)^{2})
Use binomial theorem \left(a-b\right)^{2}=a^{2}-2ab+b^{2} to expand \left(2-x\right)^{2}.
\frac{\mathrm{d}}{\mathrm{d}x}(\left(\sqrt{29-4x+x^{2}}\right)^{2})
Add 4 and 25 to get 29.
\frac{\mathrm{d}}{\mathrm{d}x}(29-4x+x^{2})
Calculate \sqrt{29-4x+x^{2}} to the power of 2 and get 29-4x+x^{2}.
-4x^{1-1}+2x^{2-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
-4x^{0}+2x^{2-1}
Subtract 1 from 1.
-4x^{0}+2x^{1}
Subtract 1 from 2.
-4x^{0}+2x
For any term t, t^{1}=t.
-4+2x
For any term t except 0, t^{0}=1.