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Differentiate w.r.t. x
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\left(\frac{Azy^{4}}{z^{-3}y_{2}x^{2}}\right)^{-1}
Cancel out yx^{2} in both numerator and denominator.
\left(\frac{Ay^{4}z^{4}}{y_{2}x^{2}}\right)^{-1}
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{\left(Ay^{4}z^{4}\right)^{-1}}{\left(y_{2}x^{2}\right)^{-1}}
To raise \frac{Ay^{4}z^{4}}{y_{2}x^{2}} to a power, raise both numerator and denominator to the power and then divide.
\frac{A^{-1}\left(y^{4}\right)^{-1}\left(z^{4}\right)^{-1}}{\left(y_{2}x^{2}\right)^{-1}}
Expand \left(Ay^{4}z^{4}\right)^{-1}.
\frac{A^{-1}y^{-4}\left(z^{4}\right)^{-1}}{\left(y_{2}x^{2}\right)^{-1}}
To raise a power to another power, multiply the exponents. Multiply 4 and -1 to get -4.
\frac{A^{-1}y^{-4}z^{-4}}{\left(y_{2}x^{2}\right)^{-1}}
To raise a power to another power, multiply the exponents. Multiply 4 and -1 to get -4.
\frac{A^{-1}y^{-4}z^{-4}}{y_{2}^{-1}\left(x^{2}\right)^{-1}}
Expand \left(y_{2}x^{2}\right)^{-1}.
\frac{A^{-1}y^{-4}z^{-4}}{y_{2}^{-1}x^{-2}}
To raise a power to another power, multiply the exponents. Multiply 2 and -1 to get -2.