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Evaluate
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Differentiate w.r.t. x
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\frac{4x^{-9}y^{2}z^{5}}{3z^{-8}x^{-4}y^{-2}}
Cancel out 5 in both numerator and denominator.
\frac{4x^{-9}y^{4}z^{13}}{3x^{-4}}
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{4y^{4}z^{13}}{3x^{5}}
To divide powers of the same base, subtract the numerator's exponent from the denominator's exponent.
\frac{\mathrm{d}}{\mathrm{d}x}(\frac{20y^{2}z^{5}y^{2}z^{8}}{15}x^{-9-\left(-4\right)})
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{\mathrm{d}}{\mathrm{d}x}(\frac{4y^{4}z^{13}}{3}x^{-5})
Do the arithmetic.
-5\times \frac{4y^{4}z^{13}}{3}x^{-5-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
\left(-\frac{20y^{4}z^{13}}{3}\right)x^{-6}
Do the arithmetic.