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\left(\frac{6}{36}+\frac{1}{36}-\frac{1}{4}+\frac{1}{12}\right)\left(-48\right)
Least common multiple of 6 and 36 is 36. Convert \frac{1}{6} and \frac{1}{36} to fractions with denominator 36.
\left(\frac{6+1}{36}-\frac{1}{4}+\frac{1}{12}\right)\left(-48\right)
Since \frac{6}{36} and \frac{1}{36} have the same denominator, add them by adding their numerators.
\left(\frac{7}{36}-\frac{1}{4}+\frac{1}{12}\right)\left(-48\right)
Add 6 and 1 to get 7.
\left(\frac{7}{36}-\frac{9}{36}+\frac{1}{12}\right)\left(-48\right)
Least common multiple of 36 and 4 is 36. Convert \frac{7}{36} and \frac{1}{4} to fractions with denominator 36.
\left(\frac{7-9}{36}+\frac{1}{12}\right)\left(-48\right)
Since \frac{7}{36} and \frac{9}{36} have the same denominator, subtract them by subtracting their numerators.
\left(\frac{-2}{36}+\frac{1}{12}\right)\left(-48\right)
Subtract 9 from 7 to get -2.
\left(-\frac{1}{18}+\frac{1}{12}\right)\left(-48\right)
Reduce the fraction \frac{-2}{36} to lowest terms by extracting and canceling out 2.
\left(-\frac{2}{36}+\frac{3}{36}\right)\left(-48\right)
Least common multiple of 18 and 12 is 36. Convert -\frac{1}{18} and \frac{1}{12} to fractions with denominator 36.
\frac{-2+3}{36}\left(-48\right)
Since -\frac{2}{36} and \frac{3}{36} have the same denominator, add them by adding their numerators.
\frac{1}{36}\left(-48\right)
Add -2 and 3 to get 1.
\frac{-48}{36}
Multiply \frac{1}{36} and -48 to get \frac{-48}{36}.
-\frac{4}{3}
Reduce the fraction \frac{-48}{36} to lowest terms by extracting and canceling out 12.