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Differentiate w.r.t. x
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\frac{1^{-2}}{\left(10x^{2}y^{-5}\right)^{-2}}\times \left(\frac{20}{x^{-23}y^{12}}\right)^{-1}
To raise \frac{1}{10x^{2}y^{-5}} to a power, raise both numerator and denominator to the power and then divide.
\frac{1^{-2}}{\left(10x^{2}y^{-5}\right)^{-2}}\times \frac{20^{-1}}{\left(x^{-23}y^{12}\right)^{-1}}
To raise \frac{20}{x^{-23}y^{12}} to a power, raise both numerator and denominator to the power and then divide.
\frac{1^{-2}\times 20^{-1}}{\left(10x^{2}y^{-5}\right)^{-2}\left(x^{-23}y^{12}\right)^{-1}}
Multiply \frac{1^{-2}}{\left(10x^{2}y^{-5}\right)^{-2}} times \frac{20^{-1}}{\left(x^{-23}y^{12}\right)^{-1}} by multiplying numerator times numerator and denominator times denominator.
\frac{1\times 20^{-1}}{\left(10x^{2}y^{-5}\right)^{-2}\left(x^{-23}y^{12}\right)^{-1}}
Calculate 1 to the power of -2 and get 1.
\frac{1\times \frac{1}{20}}{\left(10x^{2}y^{-5}\right)^{-2}\left(x^{-23}y^{12}\right)^{-1}}
Calculate 20 to the power of -1 and get \frac{1}{20}.
\frac{\frac{1}{20}}{\left(10x^{2}y^{-5}\right)^{-2}\left(x^{-23}y^{12}\right)^{-1}}
Multiply 1 and \frac{1}{20} to get \frac{1}{20}.
\frac{\frac{1}{20}}{10^{-2}\left(x^{2}\right)^{-2}\left(y^{-5}\right)^{-2}\left(x^{-23}y^{12}\right)^{-1}}
Expand \left(10x^{2}y^{-5}\right)^{-2}.
\frac{\frac{1}{20}}{10^{-2}x^{-4}\left(y^{-5}\right)^{-2}\left(x^{-23}y^{12}\right)^{-1}}
To raise a power to another power, multiply the exponents. Multiply 2 and -2 to get -4.
\frac{\frac{1}{20}}{10^{-2}x^{-4}y^{10}\left(x^{-23}y^{12}\right)^{-1}}
To raise a power to another power, multiply the exponents. Multiply -5 and -2 to get 10.
\frac{\frac{1}{20}}{\frac{1}{100}x^{-4}y^{10}\left(x^{-23}y^{12}\right)^{-1}}
Calculate 10 to the power of -2 and get \frac{1}{100}.
\frac{\frac{1}{20}}{\frac{1}{100}x^{-4}y^{10}\left(x^{-23}\right)^{-1}\left(y^{12}\right)^{-1}}
Expand \left(x^{-23}y^{12}\right)^{-1}.
\frac{\frac{1}{20}}{\frac{1}{100}x^{-4}y^{10}x^{23}\left(y^{12}\right)^{-1}}
To raise a power to another power, multiply the exponents. Multiply -23 and -1 to get 23.
\frac{\frac{1}{20}}{\frac{1}{100}x^{-4}y^{10}x^{23}y^{-12}}
To raise a power to another power, multiply the exponents. Multiply 12 and -1 to get -12.
\frac{\frac{1}{20}}{\frac{1}{100}x^{19}y^{10}y^{-12}}
To multiply powers of the same base, add their exponents. Add -4 and 23 to get 19.
\frac{\frac{1}{20}}{\frac{1}{100}x^{19}y^{-2}}
To multiply powers of the same base, add their exponents. Add 10 and -12 to get -2.
\frac{1}{20\times \frac{1}{100}x^{19}y^{-2}}
Express \frac{\frac{1}{20}}{\frac{1}{100}x^{19}y^{-2}} as a single fraction.
\frac{1}{\frac{1}{5}x^{19}y^{-2}}
Multiply 20 and \frac{1}{100} to get \frac{1}{5}.