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Differentiate w.r.t. a
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\left(32a^{8}\right)^{1}\times \frac{1}{-4a^{6}}
Use the rules of exponents to simplify the expression.
32^{1}\left(a^{8}\right)^{1}\times \frac{1}{-4}\times \frac{1}{a^{6}}
To raise the product of two or more numbers to a power, raise each number to the power and take their product.
32^{1}\times \frac{1}{-4}\left(a^{8}\right)^{1}\times \frac{1}{a^{6}}
Use the Commutative Property of Multiplication.
32^{1}\times \frac{1}{-4}a^{8}a^{6\left(-1\right)}
To raise a power to another power, multiply the exponents.
32^{1}\times \frac{1}{-4}a^{8}a^{-6}
Multiply 6 times -1.
32^{1}\times \frac{1}{-4}a^{8-6}
To multiply powers of the same base, add their exponents.
32^{1}\times \frac{1}{-4}a^{2}
Add the exponents 8 and -6.
32\times \frac{1}{-4}a^{2}
Raise 32 to the power 1.
32\left(-\frac{1}{4}\right)a^{2}
Raise -4 to the power -1.
-8a^{2}
Multiply 32 times -\frac{1}{4}.
\frac{32^{1}a^{8}}{\left(-4\right)^{1}a^{6}}
Use the rules of exponents to simplify the expression.
\frac{32^{1}a^{8-6}}{\left(-4\right)^{1}}
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{32^{1}a^{2}}{\left(-4\right)^{1}}
Subtract 6 from 8.
-8a^{2}
Divide 32 by -4.
\frac{\mathrm{d}}{\mathrm{d}a}(\frac{32}{-4}a^{8-6})
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{\mathrm{d}}{\mathrm{d}a}(-8a^{2})
Do the arithmetic.
2\left(-8\right)a^{2-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
-16a^{1}
Do the arithmetic.
-16a
For any term t, t^{1}=t.