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Differentiate w.r.t. x
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\frac{\mathrm{d}}{\mathrm{d}x}(x^{-10})
Subtract 8 from -2 to get -10.
-10x^{-10-1}
The derivative of ax^{n} is nax^{n-1}.
-10x^{-11}
Subtract 1 from -10.
x^{-10}
Subtract 8 from -2 to get -10.