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4x^{2}+12x+9-\left(5x-1\right)^{2}
Use binomial theorem \left(a+b\right)^{2}=a^{2}+2ab+b^{2} to expand \left(2x+3\right)^{2}.
4x^{2}+12x+9-\left(25x^{2}-10x+1\right)
Use binomial theorem \left(a-b\right)^{2}=a^{2}-2ab+b^{2} to expand \left(5x-1\right)^{2}.
4x^{2}+12x+9-25x^{2}+10x-1
To find the opposite of 25x^{2}-10x+1, find the opposite of each term.
-21x^{2}+12x+9+10x-1
Combine 4x^{2} and -25x^{2} to get -21x^{2}.
-21x^{2}+22x+9-1
Combine 12x and 10x to get 22x.
-21x^{2}+22x+8
Subtract 1 from 9 to get 8.
4x^{2}+12x+9-\left(5x-1\right)^{2}
Use binomial theorem \left(a+b\right)^{2}=a^{2}+2ab+b^{2} to expand \left(2x+3\right)^{2}.
4x^{2}+12x+9-\left(25x^{2}-10x+1\right)
Use binomial theorem \left(a-b\right)^{2}=a^{2}-2ab+b^{2} to expand \left(5x-1\right)^{2}.
4x^{2}+12x+9-25x^{2}+10x-1
To find the opposite of 25x^{2}-10x+1, find the opposite of each term.
-21x^{2}+12x+9+10x-1
Combine 4x^{2} and -25x^{2} to get -21x^{2}.
-21x^{2}+22x+9-1
Combine 12x and 10x to get 22x.
-21x^{2}+22x+8
Subtract 1 from 9 to get 8.