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\left(\left(x^{3}\right)^{2}+8x^{3}+16\right)\left(-4\right)x^{3}
Use binomial theorem \left(a+b\right)^{2}=a^{2}+2ab+b^{2} to expand \left(x^{3}+4\right)^{2}.
\left(x^{6}+8x^{3}+16\right)\left(-4\right)x^{3}
To raise a power to another power, multiply the exponents. Multiply 3 and 2 to get 6.
\left(-4x^{6}-32x^{3}-64\right)x^{3}
Use the distributive property to multiply x^{6}+8x^{3}+16 by -4.
-4x^{9}-32x^{6}-64x^{3}
Use the distributive property to multiply -4x^{6}-32x^{3}-64 by x^{3}.
\left(\left(x^{3}\right)^{2}+8x^{3}+16\right)\left(-4\right)x^{3}
Use binomial theorem \left(a+b\right)^{2}=a^{2}+2ab+b^{2} to expand \left(x^{3}+4\right)^{2}.
\left(x^{6}+8x^{3}+16\right)\left(-4\right)x^{3}
To raise a power to another power, multiply the exponents. Multiply 3 and 2 to get 6.
\left(-4x^{6}-32x^{3}-64\right)x^{3}
Use the distributive property to multiply x^{6}+8x^{3}+16 by -4.
-4x^{9}-32x^{6}-64x^{3}
Use the distributive property to multiply -4x^{6}-32x^{3}-64 by x^{3}.