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Differentiate w.r.t. x
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\frac{\mathrm{d}}{\mathrm{d}x}(\left(x^{\frac{-2}{3}}\right)^{\frac{3}{4}})
To raise a power to another power, multiply the exponents. Multiply \frac{3}{5} and \frac{5}{4} to get \frac{3}{4}.
\frac{\mathrm{d}}{\mathrm{d}x}(\left(x^{-\frac{2}{3}}\right)^{\frac{3}{4}})
Fraction \frac{-2}{3} can be rewritten as -\frac{2}{3} by extracting the negative sign.
\frac{\mathrm{d}}{\mathrm{d}x}(x^{-\frac{1}{2}})
To raise a power to another power, multiply the exponents. Multiply -\frac{2}{3} and \frac{3}{4} to get -\frac{1}{2}.
-\frac{1}{2}x^{-\frac{1}{2}-1}
The derivative of ax^{n} is nax^{n-1}.
-\frac{1}{2}x^{-\frac{3}{2}}
Subtract 1 from -\frac{1}{2}.